alcoholism thiamine
Thiamine deficiency difficult question?
Thiamin (vitamin B1) is an important cofactor in one of the reactions in the Krebs cycle and also the reaction that converts Pyruvate to acetyl-CoA. It is usually found in the diet in yeast, pork, vegetables, cereals and rice. It can decom deficiency during malnutrition or Conditions lead to malnutrition, such as alcoholism, HIV, and anorexia. QUESTION: How does the cellular respiration will be affected? What symptoms are observed?
Thiamine stores can be depleted within 1 month, but it is quite rare in those days. When this happens, it is usually due to insufficient caloric intake (starving.) avoided in North America, many alcoholic beverages, fortified with B1 exactly on this issue. Depending on the severity of alcoholism, the fortified B1 may or may not be sufficient be. Frank B1 deficiency is as beri-beri. Classic presentation includes: resting tachycardia (racing heart), weakness, decreased tendon reflexes, and symmetrical, some people in the development of peripheral neuropathy (usually starts with numbness / tingling in the fingers and toes.) would be a further representation "Wernicke's encephalopathy" - That presents with an ordered sequence of the onset of symptoms: vomiting, involuntary eye movements, fever, ataxia (uncontrolled movement of skeletal muscle), and progressive mental impairment. Some of the symptoms can be reversed, many of the neurological consequences are durable with the treatment.
